The caution the drug should be administered to patients who have indicated an allergy to sulfasalazine, as well as possible reactions of hypersensitivity to salicylates.
Caution should be exercised when administering the drug in patients with impaired liver and kidney function, as the decrease in the rate of elimination and increased systemic concentration of mesalazine increases the risk of kidney damage.
Application of pregnancy and breastfeeding period
The preparation of what is trenbolone acetate may be used during pregnancy only if the expected benefit prevails over potential risk to the fetus. In the last 2-4 weeks of pregnancy should stop taking the drug.
Mesalazine crosses the placental barrier and is excreted in breast milk. Therefore, at the time of taking the drug breast-feeding should be discontinued.
Dosage and administration:
1 suppository 1-2 times a day. The maximum daily dose is 6-8 suppositories.
Before the introduction of the suppository should be emptied bowels.
To ensure hygiene of manipulation, use a rubber fingertip.
Suppository inserted into the rectum prior to the termination resistance of the muscular sphincter. If within 10 minutes after administration will indicate a suppository, the suppository should enter another. For ease of use, a suppository can be moistened with water.
The average duration of treatment is 8-12 weeks, the criterion of the effectiveness of treatment is to achieve clinical and endoscopic remission. The maximum duration of the treatment, including supportive and anti-relapse therapy is not limited. Guests can also celebrate local reactions, such as itching, discomfort, urgency to defecate.
If any of these instructions, the side “effects are compounded, or if you notice any other side effects what is trenbolone acetate not specified in the instructions, inform your doctor .
Cases of overdose are rare. Symptoms include nausea, vomiting, gastralgia, weakness, drowsiness. There are no specific antidote.
Treatment is symptomatic, coupled with the control functions of the liver and kidneys. In the case of acidosis, alkalosis, dehydration, or you want to restore kislotnoschelochnoy and water-electrolyte balance.If there are signs of hypoglycemia should take glucose.
Interaction with other drugs
Mesalazin enhances the hypoglycemic effect of sulfonylurea derivatives, ulzerogennosti corticosteroids, methotrexate toxicity. Reduces the activity of furosemide, spironolactone, sulfonamides, rifampicin, increases the effects of anticoagulants. It increases the effectiveness of blockers of tubular secretion. It slows down the absorption of cyanocobalamin (vitamin B 12 ).
The medical monitoring is necessary in patients with impaired lung function, in particular, suffer from asthma. In case of acute symptoms of intolerance to the drug (muscle cramps, abdominal pain, fever, severe headache and skin rash) or signs of abnormalities in the liver and / or kidney disease taking the drug what is trenbolone acetate should be discontinued!
Throughout the course of treatment with should regularly control the rate of creatinine in the blood. buy anabolic steroids online bruce lee’s workout anabolic steroids online uk